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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭
United kingdom yorkshire
April 1
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A myPBCteam Member

Hi Cindy, I wish I had an answer for you. I don't but I wanted to share my skin story with you. I was diagnosed with PBC in 2024 and am taking Urso and Iqirvo. Last summer I noticed a few dark quarter sized spots on my legs and later a couple starting on my wrists. They looked irregular, and resembled bruises - although I had no reason to have bruises. I showed them to my GI specialist who had no idea what they were and ordered a skin rash cream. I felt annoyed because these definitely did not resemble a rash. But I used the cream for a couple months and there was no effect either way - the spots did not get bigger, nor did they go away. I had an already scheduled appointment to my dermatologist and showed it to her. She also had no idea what the spots were. I was tempted to visit a hematologist thinking it could be a number of blood disorders causing it. (I am a critical care nurse), but finally after about 5 months of having the spots since their onset, they finally started to fade, and now are completely gone. I have no answer to why I had them. I hope you get some answers because it is worrisome to get spots and not know what they are or what causes them.

April 2
A myPBCteam Member

Awwww, thank you so much 💓 you are wonderful ❤️

April 6
myPBCteam

It sounds like you're noticing dark areas on parts of your arms. While this isn't typically listed as a common symptom of PBC, it's important to discuss any skin changes with your healthcare provider.

PBC can cause various skin-related symptoms, though they usually present differently. The most common skin-related issues Show Full Answer

It sounds like you're noticing dark areas on parts of your arms. While this isn't typically listed as a common symptom of PBC, it's important to discuss any skin changes with your healthcare provider.

PBC can cause various skin-related symptoms, though they usually present differently. The most common skin-related issues with PBC include:

* Jaundice (yellowing of the skin and eyes) due to bile buildup
* Itching, which can sometimes lead to darkened skin from scratching
* Dry skin

Dark patches on the skin could be related to many factors, including sun exposure, medication side effects, or other conditions. Since PBC can affect how your liver processes certain substances, any unusual skin changes should be evaluated by your doctor.

If you're also experiencing other symptoms like fatigue, itching, or changes in urine color, make sure to mention these as well. Your healthcare provider can determine if the darkening is related to PBC or something else that needs attention.

April 1

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