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June 14
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Wishing you all the best for tomorrow's CT scan — it's good that your care team is keeping a close eye on things.

Repatha is a PCSK9 inhibitor, a newer type of cholesterol medication that helps the liver clear "bad" cholesterol from the blood. It's typically given as an injection every few months, often at a doctor's Show Full Answer

Wishing you all the best for tomorrow's CT scan — it's good that your care team is keeping a close eye on things.

Repatha is a PCSK9 inhibitor, a newer type of cholesterol medication that helps the liver clear "bad" cholesterol from the blood. It's typically given as an injection every few months, often at a doctor's office.

For people with PBC, high cholesterol can be a real concern because when bile doesn't flow properly, the body absorbs less cholesterol but the liver may compensate by producing more — a combination that can raise cholesterol levels over time. Managing cholesterol with PBC often involves a stepped approach:

- Statins (like atorvastatin or simvastatin) are usually tried first
- PCSK9 inhibitors like Repatha may be added or substituted if statins aren't enough
- UDCA, a common PBC treatment, can also help lower cholesterol by addressing the underlying bile flow issue
- Fenofibrate, another PBC medication, may also help with cholesterol levels

Some myPBCteam members have shared their experiences with statins and other cholesterol treatments, so you're definitely not alone in navigating this.

It's worth having a detailed conversation with your doctor about whether Repatha is the right fit given your specific situation, especially with the aortic calcium plaque findings.

June 14

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