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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does anyone take medication for stress, and if so what do you take. I know I have to speak with my dr about this

A myPBCteam Member asked a question 💭
Maine, NY
October 5
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A myPBCteam Member

I am on Wellbutrin for anxiety and stress, it helps, it’s not a cure but it does help. I’ve tried other meds for this in the past, but so far Wellbutrin works better for me. Hope this helps❤️

October 5
myPBCteam

Managing stress and anxiety with PBC is really important, as stress can interfere with how well treatment works. While there aren't PBC-specific medications just for stress and anxiety, there are some options worth discussing with a hepatologist.

One medication that has been studied in PBC is sertraline, an SSRI (a type of Show Full Answer

Managing stress and anxiety with PBC is really important, as stress can interfere with how well treatment works. While there aren't PBC-specific medications just for stress and anxiety, there are some options worth discussing with a hepatologist.

One medication that has been studied in PBC is sertraline, an SSRI (a type of antidepressant that also helps with anxiety). Interestingly, it was originally looked at for PBC-related itching, but it also supports mood and stress management.

A few important things to keep in mind:

- Always check any new medication or supplement with your hepatologist, since the liver processes most medications
- SSRIs like sertraline may be a reasonable option to explore, but your doctor will weigh the benefits against any liver-related risks
- Non-medication approaches can also make a real difference alongside any prescribed treatment Some lifestyle strategies that can help reduce stress and anxiety with PBC include:

- Gentle exercise, even short walks
- Practicing good sleep habits
- Reducing unnecessary stressors where possible
- Relaxing activities like massage, acupuncture, or at-home spa routines
- Staying connected with a supportive community

As one myPBCteam member shared, eliminating stress from your life and prioritizing rest can actually help your treatment work better. It's always worth having an open conversation with your hepatologist about what options are safest for your specific situation.

October 5
A myPBCteam Member

Hey Ellen.
I’ve been on Effexor for some 26 yrs for stress and high anxiety. It stops us from stimulating the sympathetic nervous system. Switch's us to the parasympathetic nervous system which is calmness, rest and digest. Yoga does the exact same thing. Yoga is my lifeline because it keeps my mental health healthy. I don’t know how I did without it. Only found it about 3 yrs ago. Hope this helps. ❤️🥰🎉

October 5 (edited)
A myPBCteam Member

I can’t take SSRI’s because they cause hyper mania with my bipolar meds.
I also have Generalized Anxiety, complex PTSD and chronic stress disorder(Cortisol is in constantly high due to stressors) so I take Gabapentin because it is none addictive and has shown to lower anxiety especially if it is taken at night. Also was told I could add an extra during the day to drop me a level.
There is also magnesium citrate that can help with the stress. However with that I was told to be careful and if it made me drowsy to add it to my nighttime regimen.
I also used DBSA or NAMI (Visio, zoom) online peer support groups.

October 7 (edited)
A myPBCteam Member

Thank you Phyllis

October 5

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