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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭

I was on a med for high cholesterol prior to being treated for PBC. I was instructed to stop taking that medication. Yet cholesterol is the enemy of the bile ducts and of course my heart. So, is there a med I can take or is this also needing stricter diet control.

March 21, 2025
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A myPBCteam Member

Hi Todd, I take Fenofibrate for PBC, but it is also a drug that helps with cholesterol. My liver doctor at UCLA had me start it since it also helps with PBC. I started with 54mg that I take at night. My total cholesterol number looks high, but the separate numbers show that my good is high and the bad is low. Hope this information helps.

March 22, 2025
A myPBCteam Member

I take rosuvastatin 5mg. So its a low does. Both my GP and liver nurse practitioner Jackie are good with this med and dose. I can even go up to 10mg safely if needed. I don’t have any side effects from it so far so good.

April 5, 2025
A myPBCteam Member

I'm on cholesterol pills as well as my Urso

March 21, 2025
myPBCteam

Can cholesterol medications be safely taken with PBC treatments?

Studies have shown that statins are generally safe for people with PBC, though research is still limited. PCSK9 inhibitors appear to be safe for those with moderate liver disease. Your doctors will monitor your liver health closely while taking these Show Full Answer

Can cholesterol medications be safely taken with PBC treatments?

Studies have shown that statins are generally safe for people with PBC, though research is still limited. PCSK9 inhibitors appear to be safe for those with moderate liver disease. Your doctors will monitor your liver health closely while taking these medications. Some PBC treatments may actually help manage cholesterol levels. For example, Ursodeoxycholic acid (UDCA/Ursodiol) helps move bile and can lower total cholesterol levels by treating cholestasis. Fenofibrate is another PBC treatment that can help reduce cholesterol.

It's important to have your hepatologist review any new medications or supplements before starting them. The best approach is ensuring your general practitioner and hepatologist communicate about your treatment plan.

March 21, 2025
A myPBCteam Member

I was taking a statin and stopped when I was diagnosed. My primary dr wants me back on a statin but I don't want to take one. I had severe muscle spasm while on statins. My gastroenterologist said a statin would be okay but I am fearful of further liver damage. I have researched non statins, after 2 months of requesting my insurance approved Praluent. After insurance the cost will be $482.00 a month and I cant afford that. I have an appointment at Cleveland Clinic in July and hoping to get some answers to my questions.

March 21, 2025

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