Research shows that people with PBC commonly have other autoimmune conditions - about 32% of PBC patients have at least one additional autoimmune condition, compared to 13% of people without PBC. This higher occurrence may be due to genetic links between autoimmune diseases that affect how the immune system functions. The Show Full Answer
Research shows that people with PBC commonly have other autoimmune conditions - about 32% of PBC patients have at least one additional autoimmune condition, compared to 13% of people without PBC. This higher occurrence may be due to genetic links between autoimmune diseases that affect how the immune system functions. The most common autoimmune conditions that occur alongside PBC include:
- Sjögren's disease (affects 40-65% of PBC patients)
- Autoimmune thyroid disease (affects 10-15%)
- Scleroderma (affects 5-15%)
- Rheumatoid arthritis (affects 5-10%)
Many myPBCteam members report experiencing multiple autoimmune symptoms throughout their lives, including fatigue, dry mouth and eyes, and skin issues.
July 12, 2025