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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
January 7
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myPBCteam

Is itching on the back of your hands and wrists common with PBC?

Yes, many people with PBC experience itching in exactly the areas you're describing. Itching on the hands is actually one of the most common locations for PBC-related itch, particularly on the palms and backs of the hands.

About 73-81% of people with PBC Show Full Answer

Is itching on the back of your hands and wrists common with PBC?

Yes, many people with PBC experience itching in exactly the areas you're describing. Itching on the hands is actually one of the most common locations for PBC-related itch, particularly on the palms and backs of the hands.

About 73-81% of people with PBC experience itchy skin at some point during their disease journey. It can start years after diagnosis, just like you're experiencing now. The itching often affects the arms, legs, hands, and feet most intensely.

A myPBCteam member shared: "My left hand is itching so badly that I have scratched the top layer of skin off and it bled."

Why does this happen?

When PBC damages bile ducts, bile acids can build up in your bloodstream and reach your skin. These bile acids may trigger nerve endings that send itching signals to your brain, even without a visible rash.

What you can do:

Since you're experiencing new itching after 5 years, it's important to talk with your doctor. They can:
- Check your liver function tests
- Prescribe medications specifically for PBC-related itching (like cholestyramine, rifampin, or other options)
- Adjust your current treatment if needed

Don't wait to address this—itching can significantly affect your quality of life and sleep, but there are effective treatments available.

January 7

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