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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭
Ohio City, CO
January 11
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A myPBCteam Member

Yes HDL has been high for couple of years.

January 13
myPBCteam

Was your HDL high when diagnosed with PBC?

Many people with PBC do have high cholesterol levels at diagnosis, including elevated HDL (high-density lipoprotein or "good" cholesterol). More than 50 percent of people with PBC have extremely high fat levels in their blood, and PBC may be associated with high levels of HDL Show Full Answer

Was your HDL high when diagnosed with PBC?

Many people with PBC do have high cholesterol levels at diagnosis, including elevated HDL (high-density lipoprotein or "good" cholesterol). More than 50 percent of people with PBC have extremely high fat levels in their blood, and PBC may be associated with high levels of HDL specifically.

This happens because as PBC progresses, damaged bile ducts reduce bile flow through the liver. Since bile helps your body digest fats and absorb cholesterol from food, when bile can't flow properly, your body can't break down or remove all the cholesterol you eat. At the same time, your liver may produce more cholesterol because it thinks there isn't enough.

People with PBC may also have a unique form of cholesterol called lipoprotein X, which can interfere with standard cholesterol test results. That's why doctors often use a special test called ApoB-100 for people with PBC, as it's more specific and accounts for lipoprotein X.

If you're curious about your own cholesterol levels at diagnosis, it might help to review your initial lab results with your hepatologist.

January 11

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