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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Wanting to I know if it is ok to take fenofibrate or Tricor to lower cholesterol. I can't tolerate statins.

A myPBCteam Member asked a question 💭
Wheeling, WV
March 19
 · 
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myPBCteam

Is it safe to take fenofibrate (Tricor) for high cholesterol if you can't tolerate statins?

Yes, fenofibrate can be an option for managing cholesterol when statins aren't tolerated. It's actually used as a treatment for PBC itself and has the added benefit of helping lower cholesterol levels.

Fenofibrate works by helping Show Full Answer

Is it safe to take fenofibrate (Tricor) for high cholesterol if you can't tolerate statins?

Yes, fenofibrate can be an option for managing cholesterol when statins aren't tolerated. It's actually used as a treatment for PBC itself and has the added benefit of helping lower cholesterol levels.

Fenofibrate works by helping your liver manage bile and fat better, which addresses some of the underlying issues in PBC. Since it treats cholestasis (the bile flow problem that contributes to high cholesterol), it can help bring down your total cholesterol levels.

However, there's an important consideration: researchers aren't completely sure that fibrates provide the same protection against heart disease that statins do. This doesn't mean they're not helpful, but it's something to discuss with your doctor when weighing your options.

Since you're already dealing with PBC and can't tolerate statins, fenofibrate might be a good fit. Your hepatologist can help determine if it's right for your specific situation and monitor how well it's working for both your liver health and cholesterol levels.

Make sure your general practitioner and hepatologist are communicating about this decision, as they can work together to find the best approach for managing your cholesterol safely.

March 19
A myPBCteam Member

Hi there, I take fenofibrate as well I originally was prescribed it for fatigue 🤷 I also take stain as well because my numbers are high all my other tests are good but the cholesterol is bad I also went on Zepbound and am doing red light therapy and exercise a little bit days it’s hard I do a vibration plate the red light and vibration plate help with depression and anxiety but I also have a underdeveloped thyroid

March 24
A myPBCteam Member

Have you seen a PBC specialist? I have cirrhosis stage 4 and portal hypertension, taking Urso three times a day and Xifazan twice daily.

March 22
A myPBCteam Member

I take Fenofibrate my hematologist prescribed it for a fatigue and my cholesterol numbers

March 19
A myPBCteam Member

Hi Mary, I have been taking Fenofibrate for quite awhile and it does help with the cholesterol levels. The levels do jump around, but for the most part it is very helpful. I also can't take statins because it raised my liver numbers and I put on 10 lbs that I can't seem to lose. Didn't want to go thru the trial and error of trying different statins to see if they worked. I'm at a good place right now.

March 19

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