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A myPBCteam Member asked a question 💭
Brooklyn Park, MN

Are there safe supplements that could lower cholesterol without taking statins?

April 30
 · 
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myPBCteam

It's completely understandable to want options beyond statins, especially when you're already managing PBC. Some supplements are commonly discussed for cholesterol support, but with PBC, it's really important to check with your hepatologist before starting anything new — your liver is already working hard.

Here are a few Show Full Answer

It's completely understandable to want options beyond statins, especially when you're already managing PBC. Some supplements are commonly discussed for cholesterol support, but with PBC, it's really important to check with your hepatologist before starting anything new — your liver is already working hard.

Here are a few supplements that come up in the conversation, along with important cautions for people with PBC:

- Omega-3 / Fish oil — May support cholesterol levels, but can thin the blood and increase bleeding risk, especially if you're on blood thinners. Can also cause nausea or digestive upset.
- Milk thistle — Sometimes used for liver and cholesterol support, but it may interfere with cholesterol medications and could cause stomach upset.
- Probiotics — Support gut health and nutrient absorption, which matters a lot with PBC.
- Vitamins D, A, E, and K — People with PBC often have trouble absorbing fat-soluble vitamins, so these may need replacing. One thing worth knowing: your existing PBC treatment, like UDCA (ursodiol), may already help lower cholesterol by addressing the underlying cause. Fenofibrate is another option some doctors use alongside PBC treatment.

As one myPBCteam member wisely put it — make sure your GP and hepatologist are talking to each other, and always run new supplements by your hepatologist first. They really are best placed to guide you here.

April 30

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