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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭
Sweden

I am strength training to support health with pbc and also as perimenopausal. I have read of benefits of creatine for body, strength and brain. I was curious whether it is ok to take it 5 or 10mg a day if you have PBC?

May 17
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A myPBCteam Member

Just a quick search in PubMed came up with this:
https://onlinelibrary.wiley.com/doi/full/10.100...

Not the same as PBC but interesting in that it’s related to another liver disease:
https://www.sciencedirect.com/science/article/p...

I think the source of the creatine, since it is a supplement, matters greatly in overall safety

https://www.sciencedirect.com/science/article/pii/S0024320522007640
https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.3151
May 17
myPBCteam

Strength training is a great choice for supporting bone density and overall health with PBC — so kudos for being proactive!

Creatine isn't specifically covered in PBC-focused research, but there are some important general cautions worth knowing about supplements and PBC:

- High doses of any supplement can potentially Show Full Answer

Strength training is a great choice for supporting bone density and overall health with PBC — so kudos for being proactive!

Creatine isn't specifically covered in PBC-focused research, but there are some important general cautions worth knowing about supplements and PBC:

- High doses of any supplement can potentially strain the liver
- Supplements can interact with medications used to manage PBC
- It's always best to introduce any new supplement slowly
- Your hepatologist or doctor should always be consulted before starting

Creatine is processed by the kidneys and liver, which makes checking with your doctor especially important when you have PBC. The good news is that strength training itself — even without supplements — is strongly recommended for people with PBC. It helps:

- Build and maintain bone density, reducing osteoporosis risk
- Improve muscle mass and strength
- Support better mood and mental health
- Improve overall energy levels

Your doctor or a registered dietitian nutritionist familiar with PBC would be the best people to advise on whether creatine is safe for your specific situation, liver function levels, and any medications you're currently taking.

May 17

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