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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
May 23
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myPBCteam

Mouth pain and shortness of breath are not listed among the commonly known side effects of ursodiol, and these symptoms deserve prompt attention. Please reach out to your doctor or seek medical care as soon as possible — especially regarding the shortness of breath, which should never be ignored. The more commonly reported Show Full Answer

Mouth pain and shortness of breath are not listed among the commonly known side effects of ursodiol, and these symptoms deserve prompt attention. Please reach out to your doctor or seek medical care as soon as possible — especially regarding the shortness of breath, which should never be ignored. The more commonly reported side effects of ursodiol include:

- Diarrhea
- Stomach pain
- Nausea
- Dizziness
- Back pain
- Changes in stool
- Loss of appetite

Mouth pain and shortness of breath fall outside of these, which is why it's really important to flag these specific symptoms with your healthcare provider right away. They can determine whether these are related to ursodiol, PBC itself, or something else that needs attention.

Don't wait on this one — shortness of breath in particular is something your doctor needs to know about quickly.

May 23
A myPBCteam Member

If a person has one autoimmune disease then they have at least another one. I have sjogrens and it’s more bothersome than PBC. I’m slowly losing my teeth even with great dental hygiene.
But that’s ok there’s worse out there!

Update:
Hi Donna
I really didn’t answer your question. I’d see the fam doc re the SOB and sore mouth.
Best!!

May 26 (edited)
A myPBCteam Member

Hi Emily. You and I have been on Urso about the same amt of time. Like you I have no issues!

May 31
A myPBCteam Member

This is concerning. I agree with the team. I’ve been on Urso for 34 years without any issues

May 31
A myPBCteam Member

I didn't experience that so far.

May 30

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