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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭
Florida, NY
June 4
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Yes, PBC can potentially contribute to gallbladder enlargement. Here's how it connects:

PBC damages the bile ducts in the liver, which can cause bile to back up and build up rather than flowing freely. This buildup can lead to blockages, and over time, bile may harden into gallstones. Gallstones can then cause inflammation Show Full Answer

Yes, PBC can potentially contribute to gallbladder enlargement. Here's how it connects:

PBC damages the bile ducts in the liver, which can cause bile to back up and build up rather than flowing freely. This buildup can lead to blockages, and over time, bile may harden into gallstones. Gallstones can then cause inflammation of the gallbladder, which may result in swelling or enlargement. It's worth noting that an enlarged liver (hepatomegaly) is also very common with PBC, affecting around 75% of people in the early stages. So if imaging picked up something "oversized" in that area, it's worth clarifying with your doctor whether it's the gallbladder, the liver, or both being flagged.

Either way, it's a good idea to bring this up with your healthcare team so they can investigate further and adjust your care plan if needed.

June 4

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