You're welcome! My MRI showed stage 0-1 (normal fibrosis or mild inflammation), while my fibroscan suggested severe scarring. I was formally diagnosed in early 2025 but I believe it went undetected for a handful of years.

Hi Andrea, I had a similar situation last year where I felt good with the medications. And bloodwork leading up to my most recent fibroscan suggested I was in the very early stages. However, when I saw the results of the scan it showed levels consistent with stage 4, which made no sense. My doctor immediately questioned it and scheduled a MRI for a more accurate reading. Needless to say, the fibroscan was completely off-base and my request will be to have an MRI going forward. It seems there is too much variability with the fibroscan based on what I've read (and watching how they did it). Long story short, it might be worth asking to have an MRI to confirm the results before going down a rabbit hole (which I did...). Good luck!

Yes, I get MRI's twice a year now, with contrast, and I'll have a third liver biopsy next year....still considered the gold standard for assessing level of scarring, I guess! I'm an overlap syndrome patient, too, so I also have AIH which only exacerbates the problem 😵‍💫
And yes, always nerve-wracking, no matter the test!

Hi Andrea, My experience was similar to the others in that I was having regular blood work and a liver biopsy which showed a constant F2/F3. Then I had a fibroscan which showed me in complete cirrhosis, prompting a follow-up 2nd biopsy which showed F2/3. So, we've dispensed with that test altogether!

Thank you so much for your reply!! What did your MRI show? And may I ask, how long have you had PBC?
Youre so right about not going down the rabbit hole! Buts so hard not to do lol. I appreciate your response so much!