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Obviously this info is simply just for interest / curiosity and one should always speak to their specialist care team before taking any supplements.
How Might CoQ10 Help with PBC?
1 Fighting CoQ10 Deficiency
Studies published in journals like Hepatology show that patients with untreated PBC often have a severe deficiency in plasma CoQ10 levels. This drop happens because toxic bile acids build up in the liver and disrupt normal metabolic processes. Taking a supplement can help restore these… read more
Answer Summary
Members explored whether CoQ10 helps with PBC symptoms like fatigue and itching, sharing both personal experiences and research findings.... Read more
Update - PBC Foundation pbc medical specialist Dr Martin Weltman said no evidence to support CoQ10 as beneficial.
I have posed a question about this for Professor David Jones at an online Q and A, I will report back and share what he says.
Both myself and my partner are taking CoQ10. He has had ongoing peridontial/gum issues for the last 3 years with no resolution. I found a couple of studies linking CoQ10 administration (200mg over 12 weeks) to improved gum/peridontal health. One month after using the CoQ10 his gums are the best that they've ever been (no more abscesses, bleeding while flossing, inflammation, etc). It's wild how quickly that started. I did have him draw a baseline prior to supplementation and in the US he was within conventional "normal" values however functional medicine providers want you to be higher. It is a master antioxidant that also supports mitochondrial health and I think there are more we don't know about it. It was studied extensively in cardiac health as Vicki said but it also has implications for many other settings.
https://www.ncbi.nlm.nih.gov/books/NBK531491/
https://www.mdpi.com/2076-3921/10/8/1325
https://pmc.ncbi.nlm.nih.gov/articles/PMC8150987/
Hi @A myPBCteam Member
CQ10 is one of the supplements I take. Have read some studies on benefits and added it to my medications at hs. Thanks for the reminder!
That is great to know!!! Thanks Pippa🥰
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