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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

How dangerous to have pbc with osteoporosis?

A myPBCteam Member asked a question 💭

Hi, I am 30 years old. Recently I have diagnosed pbc and the medicines are doing well. But few days before I had dexa scan that showed I have spine osteoporosis which score is -2.6 but I have no back pain or no symptoms.
Anyone here have osteoporosis and taking bisphosphonate? Also if yes is there any jaw or teeth problem occurred? I am very stressed
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August 27
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A myPBCteam Member

I don't know much about osteoporosis learning about it. Ursocol is working good for me. How are you finding it? I am also very active but this liver condition maybe is the cause that osteoporosis occurs. But hope for the best.

September 2
A myPBCteam Member

I was just recently diagnosed in June with PBC. I’m 51 years old not in menopause yet and I also just got the Dexa scan and was at -2.76 and have osteoporosis in my spine and neck! I had no idea as I’m very active, I strength train, play tennis, exercise, etc. I’m also very hesitant to start osteoporosis medicine for the same reason the dental and other concerns. I have started ursidiol but haven’t had my labs done yet to see if it’s working. I’m also very concerned.

September 1
myPBCteam

First of all, take a breath — it's completely understandable to feel stressed, but the fact that your PBC medications are working well and you caught the osteoporosis early is genuinely good news. Being proactive puts you in a strong position.

PBC can make it harder for your body to absorb fat-soluble vitamins like vitamin Show Full Answer

First of all, take a breath — it's completely understandable to feel stressed, but the fact that your PBC medications are working well and you caught the osteoporosis early is genuinely good news. Being proactive puts you in a strong position.

PBC can make it harder for your body to absorb fat-soluble vitamins like vitamin D, which is a key reason why osteoporosis is more common in people with PBC. People with PBC are about four times more likely to develop osteoporosis than those without it. The good news is there are real, effective ways to manage this. Your doctor may recommend:

- Vitamin D and calcium supplements to support bone strength
- Bisphosphonate medications to slow bone loss
- Weight-bearing exercises like walking
- Strength training to build muscle mass around bones
- Balance and stability exercises to reduce fall risk
- Gentle movement like Pilates or yoga to support the spine

It's really important to speak with your hepatologist before starting any new supplements or medications. Regarding bisphosphonates and jaw or dental concerns — this is a known question worth raising directly with your doctor, as they can assess your individual risk and monitor you appropriately. Many myPBCteam members manage osteoporosis alongside PBC successfully.

Since you have no symptoms right now, early treatment gives you the best chance of protecting your bone health long-term. You're asking exactly the right questions! 💪

August 27

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