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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭
Deutschland

Bei mir hat sich der AP Leber Wert verbessert und
die
Fettvertauung! Keine
Nebenwirkungen😀

January 15
 · 
Reactions
myPBCteam

What experiences have you had with the new medication seladelpar? For me, my ALP liver value improved and fat digestion! No side effects 😀

That's wonderful to hear your ALP levels improved and you're tolerating seladelpar well! Your experience aligns with what clinical trials have shown.

Seladelpar (Livdelzi) was approved Show Full Answer

What experiences have you had with the new medication seladelpar? For me, my ALP liver value improved and fat digestion! No side effects 😀

That's wonderful to hear your ALP levels improved and you're tolerating seladelpar well! Your experience aligns with what clinical trials have shown.

Seladelpar (Livdelzi) was approved in 2024 and has demonstrated several benefits for PBC management:

- Lower alkaline phosphatase (ALP) levels
- Reduced bilirubin levels
- Less reported fatigue, sleep problems, and itching

In clinical trials, about 25% of people saw their ALP levels return to normal, and the medication significantly reduced itching for many. Most people tolerated it well without serious side effects.

The most commonly reported side effects include:
- Headache
- Abdominal pain
- Nausea
- Bloating and feeling full

It's great that you're experiencing improvements without side effects! Every person responds differently to medications, so your positive experience is encouraging. Keep monitoring your liver values with your healthcare provider to track your progress over time.

January 15

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