Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Is anyone else struggling with hot flashes with PBC? It’s quite frequent for me. Already through meno and Dr. said not that must be PBC.

A myPBCteam Member asked a question 💭

I was diagnosed with PBC in August of 2025. Positive AMA and confirmed through liver biopsy but other liver blood work not showing elevated yet. Started on URSO which doesn’t help the symptoms for me. I struggle so much with the severe fatigue. Try and push through as much as possible and make sure to do my walks most days but if I do to much one day I end up in bed and down the next. That’s tough for me as I’ve always had such a busy life. I’m trying to rest when my body tells me to. And it is… read more

March 2
 · 
Reactions
myPBCteam

Are hot flashes and severe fatigue common with PBC, and how can you manage them?

Hot flashes aren't typically listed as a primary PBC symptom, but your doctor may be right that they could be related to your condition. PBC can affect your body in various ways, and some symptoms may be less common or not well understood yet.

Show Full Answer

Are hot flashes and severe fatigue common with PBC, and how can you manage them?

Hot flashes aren't typically listed as a primary PBC symptom, but your doctor may be right that they could be related to your condition. PBC can affect your body in various ways, and some symptoms may be less common or not well understood yet.

The severe fatigue you're experiencing is one of the most common PBC symptoms. About 50 percent of people with PBC experience fatigue, and 20 percent have severe fatigue that significantly affects quality of life. As you've discovered, this exhaustion doesn't always improve with rest and can be debilitating.

You're doing the right thing by listening to your body and resting when needed. Here are some strategies that may help:

* Continue your walks when possible, as gentle activity can help with energy
* Pace yourself and avoid overexertion on good days to prevent crashes the next day
* Try eating smaller, more frequent meals instead of large ones
* Focus on whole foods like fruits, vegetables, whole grains, and lean proteins
* Consider foods rich in B vitamins, iron, and fat-soluble vitamins (A, D, E, K) which can support energy levels

Since URSO isn't helping your symptoms yet, stay in close communication with your doctor. They can monitor your liver function and discuss whether additional treatments might help manage your fatigue and other symptoms.

March 2

Related Questions

View All

Did you get offered a Dexa Scan at diagnosis?

A myPBCteam Member asked a question 💭
Sweden
May 21 (edited)

Can You Be AMA-Positive and Not Have PBC?
Can PBC Be Misdiagnosed?
4 Vitamins for Liver Health With PBC