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A myPBCteam Member asked a question 💭
Scotland, AR
March 12
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Are you more likely to develop skin issues with cirrhosis and PBC?

Yes, skin changes are quite common with PBC. About 40 percent of people with PBC experience various skin symptoms. When PBC progresses to cirrhosis, these skin issues can become more pronounced.

Common skin changes you might notice include:

* Dry, itchy Show Full Answer

Are you more likely to develop skin issues with cirrhosis and PBC?

Yes, skin changes are quite common with PBC. About 40 percent of people with PBC experience various skin symptoms. When PBC progresses to cirrhosis, these skin issues can become more pronounced.

Common skin changes you might notice include:

* Dry, itchy skin (pruritus) - often one of the first symptoms
* Jaundice - yellowing of the skin and eyes from bilirubin buildup
* Hyperpigmentation - darkening of the skin unrelated to sun exposure
* Xanthomas - small, waxy bumps around the eyes or on joints
* Spider angiomas - red blood vessels under the skin that look like spider webs
* Easy bruising and bleeding
* Thinning or cracking skin

The skin problems happen because damaged bile ducts cause bile to build up in your organs and bloodstream instead of flowing properly. Reduced liver function can also trigger or worsen inflammatory skin conditions like eczema.

As cirrhosis develops, portal hypertension (high blood pressure in the portal vein) can cause additional skin symptoms like spider angiomas and visible swollen veins.

Working closely with your doctor to manage PBC and slow disease progression may help reduce these skin-related symptoms.

March 12

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