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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭
Wagga Wagga, AU
May 21
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That's a great question to be asking before taking anything new — your liver will thank you for being cautious!

Agemate is an NAD+ supplement that typically contains ingredients like NMN (nicotinamide mononucleotide), resveratrol, and other compounds. Since PBC affects the liver, it's really important to check with your Show Full Answer

That's a great question to be asking before taking anything new — your liver will thank you for being cautious!

Agemate is an NAD+ supplement that typically contains ingredients like NMN (nicotinamide mononucleotide), resveratrol, and other compounds. Since PBC affects the liver, it's really important to check with your hepatologist before starting any new supplement, even ones marketed as "natural" or wellness-focused.

Here's why this matters with PBC:

- Many supplements are processed by the liver, which is already under stress with PBC
- Some ingredients can affect liver enzyme levels
- Certain compounds may interact with medications like UDCA or obeticholic acid

A myPBCteam member put it well: "I would definitely check any new medication or supplement with your hepatologist. I just feel that they're the ones who would know the answer best."

Your hepatologist can review the specific ingredients in Agemate against your current labs and treatment plan to give you a personalized answer. Don't skip that step — it's really the safest route.

May 21

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