Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
Powered By
Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭
Belfast, UK

I've been on urso since January all seems to be going well but last few weeks I'm so fatigued had the cold for weeks with constant sinus problems and bloods have risen for the first time since the medication I'm scared it's not working

June 10
 · 
Be the first to react
myPBCteam

It's completely understandable to feel scared when you notice changes like rising blood results — that kind of uncertainty is really tough. The good news is that a temporary rise doesn't necessarily mean ursodiol has stopped working for you.

A prolonged cold and sinus infection can actually cause inflammation in the body Show Full Answer

It's completely understandable to feel scared when you notice changes like rising blood results — that kind of uncertainty is really tough. The good news is that a temporary rise doesn't necessarily mean ursodiol has stopped working for you.

A prolonged cold and sinus infection can actually cause inflammation in the body, which may temporarily affect liver blood results. Fatigue is also a very common symptom of fighting off an infection, so some of what you're feeling could be related to being unwell rather than the medication losing effectiveness. Ursodiol doesn't work the same way for everyone, and finding the right approach can sometimes take time and adjustment. Some things worth knowing:

- Ursodiol does not cure PBC, but it can slow progression and improve liver function for many people
- Side effects and responses vary from person to person
- Dose adjustments are sometimes needed to get the best results

The most important step right now is to contact your doctor and share your concerns. Let them know about your recent illness alongside the rising blood results — they can look at the full picture and advise whether any changes to your treatment plan are needed. Don't adjust your medication without speaking to them first.

June 10

Related Questions

View All
A myPBCteam Member asked a question 💭
Montvale, VA

A myPBCteam Member asked a question 💭
Maine, NY