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I was told that it helps protect the liver.
That's a great question — are other myPBCteam members taking L-glutathione, and could it help protect the liver with PBC?
L-glutathione is a powerful antioxidant that your body naturally produces, and it does play a role in protecting liver cells from oxidative damage. However, there isn't currently specific research on Show Full Answer
I take a Liposomal formula of glutathione from a brand called Research Nutritionals but another brand that was highly suggested was Quicksilver (it is easier to manage, just a couple of pumps in your mouth, although must be refrigerated). It helps your liver process toxins and reduce oxidative stress. I have not checked my labs yet since taking it to see if it has decreased liver enzymes but I am due in 2 weeks.
This is not medical advice. However, Here is a study showing that glutathione is low is patients with PBC. This could suggest that supplementation could be beneficial but of course formulation and brand would be most important for efficacy given liver impairment is synthesis.
https://www.sciencedirect.com/science/article/p...
This is a study in NAC, which is a precursor to glutathione, in mice showing benefit. It does require your body to convert NAC into glutathione which might be impaired in liver disease.
https://www.tandfonline.com/doi/full/10.1080/10...
This is a study showing that glutathione reduces liver enzymes (although this is specifically ALT) in a different disease of the liver, NAFLD, but worth mentioning. https://pmc.ncbi.nlm.nih.gov/articles/PMC4536296/
I'm not taking it, but I read about it recently, it was a promotion but I haven't done any further research. I'm interested in finding out more though Teresa
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