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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myPBCteam Member asked a question 💭
Sacramento Area, CA
1 day ago
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Yes, pain is definitely associated with PBC, and it can show up in several different ways. You're not imagining it — even though some doctors may suggest the liver itself doesn't have pain receptors, the inflammation and damage to surrounding tissues can absolutely cause real discomfort. Here are the most common types of Show Full Answer

Yes, pain is definitely associated with PBC, and it can show up in several different ways. You're not imagining it — even though some doctors may suggest the liver itself doesn't have pain receptors, the inflammation and damage to surrounding tissues can absolutely cause real discomfort. Here are the most common types of pain people with PBC experience:

- Liver area pain — A dull, achy feeling in the upper right abdomen, sometimes spreading to the back or shoulder blades
- Sharp or intermittent pain — Some people feel sharp pain that comes and goes
- Joint pain — Inflammation can affect joints throughout the body
- Abdominal pain — Digestive issues like fat malabsorption can cause stomach cramps
- Swelling-related pain — Fluid buildup or edema can cause pain from fingers to toes
- Bone pain — PBC can contribute to bone loss, which may cause discomfort A myPBCteam member described it well: "Sometimes I feel a hardening in the liver area and a dull pain feeling, especially when I eat."

Pain experiences vary widely from person to person. It's really important to let your healthcare provider know about any ongoing pain, as it can be a sign of disease progression and there are ways to help manage it.

1 day ago

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