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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
July 16
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It's great to hear you're doing well on your treatment combination! Iron deposits in the liver (known as hepatic iron deposition) aren't directly caused by PBC itself, but they can be associated with it in a few ways.

Here are some possible contributing factors worth discussing with your doctor:

- Liver inflammation and Show Full Answer

It's great to hear you're doing well on your treatment combination! Iron deposits in the liver (known as hepatic iron deposition) aren't directly caused by PBC itself, but they can be associated with it in a few ways.

Here are some possible contributing factors worth discussing with your doctor:

- Liver inflammation and damage β€” ongoing liver inflammation from PBC can sometimes affect how the liver processes and stores iron
- Cholestasis β€” when bile flow is impaired, it can disrupt normal liver metabolism, potentially affecting iron regulation
- Liver scarring (fibrosis) β€” as PBC progresses, changes in liver tissue can sometimes lead to iron accumulation
- Diet or supplements β€” iron-rich diets or iron supplementation can contribute to deposits

MRI elastography is a really valuable tool for monitoring liver health in PBC, so it's good that this was picked up.

This finding absolutely warrants a conversation with your hepatologist. They may want to run additional blood tests, like serum ferritin and transferrin saturation, to better understand what's driving the deposits and whether any action is needed.

You're clearly being well monitored β€” that's the best position to be in! πŸ’ͺ

July 16

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